Dapoxetine 60mg Tablet

Dapoxetine 60mg – Short-Acting SSRI / Premature Ejaculation Treatment

Dapoxetine 60mg contains Dapoxetine Hydrochloride, a short-acting ssri / premature ejaculation treatment indicated for premature ejaculation (pe) in men aged 18–64 — on-demand treatment. Integrated analysis of 5 Phase III RCTs (n=6081): dapoxetine 60mg increased IELT (intravaginal ejaculatory latency time) 3.5-fold vs placebo; FDA-reviewed but approved in EU, UK, India.

Product Information

How It Works

Short-acting selective serotonin reuptake inhibitor; peaks rapidly (1–2h) and clears within 24h; delays ejaculation via serotonergic modulation of the ejaculatory reflex — making Dapoxetine Hydrochloride effective against premature ejaculation (pe) in men aged 18–64 — on-demand treatment.

People Also Ask

What is the difference between dapoxetine 30mg and 60mg?

30mg is the starting dose, recommended for the first treatment attempts. If tolerated but insufficiently effective after several uses, increase to 60mg. In trials, 60mg produced superior IELT improvement (3.5-fold increase) versus 30mg (2.5-fold), with acceptable tolerability. Most men requiring maximum efficacy use the 60mg dose after confirming tolerability at 30mg.

How long before sex should dapoxetine 60mg be taken?

Dapoxetine 60mg should be taken 1–3 hours before anticipated sexual activity. Peak plasma concentration occurs at approximately 1–2 hours. Taking it 1 hour before is optimal. Unlike daily PE treatments (where timing doesn’t matter), dapoxetine’s on-demand nature requires planning. It does not work reliably if taken less than 1 hour before activity.

Can dapoxetine and sildenafil be taken together?

Yes — combination products (dapoxetine + sildenafil) exist because many men with premature ejaculation also experience erectile dysfunction. The combination treats both conditions simultaneously. However, orthostatic hypotension risk increases; patients should sit or lie down if dizziness occurs. Avoid alcohol, which significantly worsens orthostatic hypotension with this combination.

Is dapoxetine available in the USA?

Dapoxetine has not been FDA-approved in the USA due to concerns about cardiovascular effects (syncope/faintness) in clinical trials. It is approved and widely used in the UK, EU, Australia, South Korea, India, and many other countries. US physicians sometimes prescribe clomipramine or SSRIs off-label for premature ejaculation.

What are the side effects of dapoxetine 60mg?

Nausea is the most common side effect (affecting approximately 20% of users at 60mg). Headache, dizziness, and dry mouth also occur. Orthostatic hypotension (dizziness when standing) is a specific concern — patients should avoid sudden position changes and alcohol. Do not drive or operate machinery until the drug has cleared (24 hours). Do not take with MAO inhibitors.

Storage

Store at 15–30°C away from sunlight and moisture. Keep out of reach of children. Do not use past expiry date.